مقاله سال ۲۰۱۷

Background: Chlamydia, caused by the bacterium Chlamydia trachomatis(C. trachomatis), is the most common sexually transmitted disease. The incidence is not clear due to the asymptomatic nature of early stage of infections. The incidence of Chlamydia has not been fully investigated in the Chinese Han population. Since chronic infection with can C. trachomatis can lead to infertility in males and females, it is important to determine the impact of infection on clinical outcomes. The aim of this study is to explore the epidemiology of C. trachomatis in subfertile couples and to determine whether infections will adversely affect clinical outcomes after assisted reproduction technique (ART) treatment.

Plain English summary

One of the most common bacterial sexually transmitted disease is Chlamydia, caused by Chlamydia trachomatis (C. trachomatis), the exact incidence of Chlamydia is unknown because the infection is often asymptomatic in the early stage. The incidence of Chlamydia it has not been fully investigated in the Chinese Han population.

Since chronic infection with C. trachomatis can induce infertility in males and females. The aim of the study is to explore the epidemiology of C. trachomatis in subfertile couples and to determine adverse effects on clinical outcomes after assisted reproduction technique (ART) treatments.

A total of 30760 subfertile patients were tested for C. trachomatis in our center from January 2010 to December 2014. C. trachomatis-specific DNA was detected by Taqman PCR. The prevalence and characteristics of C. trachomatis were identified for subfertile couples and clinical outcomes were collected and analyzed. A retrospective study was performed.