مشخصات مقاله | |
ترجمه عنوان مقاله | التهاب عصبی به عنوان یک ارتباط احتمالی بین اختلال کم توجهی – بیش فعالی (ADHD) و درد |
عنوان انگلیسی مقاله | Neuroinflammation as a possible link between attention-deficit/ hyperactivity disorder (ADHD) and pain |
انتشار | مقاله سال 2021 |
تعداد صفحات مقاله انگلیسی | 8 صفحه |
هزینه | دانلود مقاله انگلیسی رایگان میباشد. |
پایگاه داده | نشریه الزویر |
نوع نگارش مقاله |
مقاله پژوهشی (Research Article) |
مقاله بیس | این مقاله بیس میباشد |
نمایه (index) | Scopus – Master Journals List – JCR – Medline |
نوع مقاله | ISI |
فرمت مقاله انگلیسی | |
ایمپکت فاکتور(IF) |
1.538 در سال 2020 |
شاخص H_index | 87 در سال 2020 |
شاخص SJR | 0.441 در سال 2020 |
شناسه ISSN | 0306-9877 |
شاخص Quartile (چارک) | Q4 در سال 2020 |
فرضیه | دارد |
مدل مفهومی | ندارد |
پرسشنامه | ندارد |
متغیر | ندارد |
رفرنس | دارد |
رشته های مرتبط | روانشناسی و پزشکی |
گرایش های مرتبط | روانپزشکی، روانشناسی رشد، مغز و اعصاب |
نوع ارائه مقاله |
ژورنال |
مجله | فرضیه های پزشکی – Medical Hypotheses |
دانشگاه | Department of Health Sciences, University West, Sweden |
کلمات کلیدی | اختلال کم توجهی – بیش فعالی، حساسیت مرکزی، التهاب عصبی، درد پاتولوژیک، اختلالات روانی |
کلمات کلیدی انگلیسی | ADHD – Central sensitization – Neuroinflammation – Pathological pain – Psychiatric disorders |
شناسه دیجیتال – doi |
https://doi.org/10.1016/j.mehy.2021.110717 |
کد محصول | E15762 |
وضعیت ترجمه مقاله | ترجمه آماده این مقاله موجود نمیباشد. میتوانید از طریق دکمه پایین سفارش دهید. |
دانلود رایگان مقاله | دانلود رایگان مقاله انگلیسی |
سفارش ترجمه این مقاله | سفارش ترجمه این مقاله |
فهرست مطالب مقاله: |
Abstract Keywords Introduction Background to hypothesis The hypothesis Evaluation of the hypothesis Consequences of the hypothesis and discussion Consent statement/Ethical approval Funding Declaration of Competing Interest References |
بخشی از متن مقاله: |
ABSTRACT Attention-deficit/hyperactivity disorder (ADHD) and pathological pain are two complex syndromes of multifactorial origin. Despite their prevalence and broad impacts, these conditions are seldom recognized and managed simultaneously. The co-existence of neuropsychiatric conditions (such as ADHD) and altered pain perception and chronic pain has been noted in children, and the comorbidity of ADHD and chronic pain is well documented in adults. Pathophysiological studies have suggested dysfunction of the dopaminergic system as a common neurochemical basis for comorbid ADHD and pain. Considerable evidence supports the role of neuroinflammation in the pathophysiology of both. We suggest that central neuroinflammation underlies altered pain perception and pain sensitization in persons with ADHD. Based on our hypothesis, targeting neuroinflammation may serve as a potential new therapeutic intervention to treat ADHD and comorbid pain in children and adolescents and a preventive strategy for the development of chronic pain in adults with ADHD. Introduction The present hypothesis considers the coexistence of somatic and mental health complaints and the relationship between them. In other words, the whole affects the parts just as much as the parts affect the whole. This is in line with a holistic (rather than reductionistic) way of thinking. Attention-deficit/hyperactivity disorder (ADHD) and chronic pain are complex syndromes of multifactorial origins. ADHD is a neurodevelopmental disorder associated with cognitive, emotional, and behavioral deficits. It is one of the most common psychiatric pathologies, with an estimated prevalence ranging from 5 to 29% in children (depending on country, year of study, and method of diagnosis) [1] and 2–5% in adults [2] worldwide. |