| مشخصات مقاله | |
| ترجمه عنوان مقاله | شواهد مبتنی بر rsfMRI برای تغییرات اتصال عملکردی در بزرگسالان مبتلا به لکنت رشدی |
| عنوان انگلیسی مقاله | rsfMRI based evidence for functional connectivity alterations in adults with developmental stuttering |
| انتشار | مقاله سال 2021 |
| تعداد صفحات مقاله انگلیسی | 12 صفحه |
| هزینه | دانلود مقاله انگلیسی رایگان میباشد. |
| پایگاه داده | نشریه الزویر |
| نوع نگارش مقاله |
مقاله پژوهشی (Research Article) |
| مقاله بیس | این مقاله بیس نمیباشد |
| نمایه (index) | Master Journal List – DOAJ – PubMed Central |
| نوع مقاله | ISI |
| فرمت مقاله انگلیسی | |
| شاخص H_index | 28 در سال 2020 |
| شاخص SJR | 0.455 در سال 2020 |
| شناسه ISSN | 2405-8440 |
| شاخص Quartile (چارک) | Q1 در سال 2020 |
| فرضیه | ندارد |
| مدل مفهومی | ندارد |
| پرسشنامه | ندارد |
| متغیر | ندارد |
| رفرنس | دارد |
| رشته های مرتبط | روانشناسی |
| گرایش های مرتبط | روانشناسی رشد |
| نوع ارائه مقاله |
ژورنال |
| مجله | هلیون – Heliyon |
| دانشگاه | Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran |
| کلمات کلیدی | لکنت رشدی مداوم (PDS)، اتصال عملکردی، رزونانس مغناطیسی عملکردی حالت استراحت، تصویربرداری (fMRI) |
| کلمات کلیدی انگلیسی | Persistent developmental stuttering (PDS) – Functional connectivity – Resting state functional magnetic resonance – imaging (fMRI) |
| شناسه دیجیتال – doi |
https://doi.org/10.1016/j.heliyon.2021.e07855 |
| کد محصول | E15777 |
| وضعیت ترجمه مقاله | ترجمه آماده این مقاله موجود نمیباشد. میتوانید از طریق دکمه پایین سفارش دهید. |
| دانلود رایگان مقاله | دانلود رایگان مقاله انگلیسی |
| سفارش ترجمه این مقاله | سفارش ترجمه این مقاله |
| فهرست مطالب مقاله: |
| Abstract Introduction Methods Results Discussion Conclusions Declarations Acknowledgments References |
| بخشی از متن مقاله: |
| ABSTRACT Persistent developmental stuttering (PDS) is defined as a speech disorder mainly characterized by intermittent involuntary disruption in normal fluency, time patterning, and rhythm of speech. Although extensive functional neuroimaging studies have explored brain activation alterations in stuttering, the main affected brain regions/ networks in PDS still remain unclear. Here, using functional magnetic resonance imaging (fMRI), we investigated resting-state whole-brain functional connectivity of 15 adults who stutter (PDS group) and 15 age-matched control individuals to reveal the connectivity abnormalities associated with stuttering. We were also interested in exploring how the severity of stuttering varies across individuals to understand the compensatory mechanism of connectivity pattern in patients showing less symptoms. Our results revealed decreased connectivity of left frontal pole and left middle frontal gyrus (MidFG) with right precentral/postcentral gyrus in stuttering individuals compared with control participants, while less symptomatic PDS individuals showed greater functional connectivity between left MidFG and left caudate. Additionally, our finding indicated reduced connectivity in the PDS group between the left superior temporal gyrus (STG) and several brain regions including the right limbic lobe, right fusiform, and right cerebellum, as well as the left middle temporal gyrus (MTG). We also observed that PDS individuals with less severe symptoms had stronger connectivity between right MTG and several left hemispheric regions including inferior frontal gyrus (IFG) and STG. The connectivity between right fronto-orbital and right MTG was also negatively correlated with stuttering severity. These findings may suggest the involvement of right MTG and left MidFG in successful compensatory mechanisms in more fluent stutterers. Introduction The interest in investigating the affected neural mechanisms in neurological and psychiatric disorders is growing fast. In hese areas, clinicians rely on therapeutic approaches, which are based on empirical observations with limited knowledge about the underlying mechanisms in the brain. Yet knowledge about the neural basis underlying the behavioral amendment of disorders could help improve the therapies. Stuttering is a speech disorder mainly characterized by repeated sounds or syllables or even words, intermittent prolongations and blocks, and disruptions in normal speech rate often accompanied by physical tension. Stuttering is categorized into three types including developmental, neurogenic, and psychogenic [1]. Developmental stuttering (DS) is very common in children under five, as children are developing their language abilities. |