مقاله انگلیسی رایگان در مورد کاربرد بیومدیکال هیدروژل کاراگینان آمیخته با نانوذرات اکسید روی – تیلور و فرانسیس ۲۰۲۲
مشخصات مقاله | |
ترجمه عنوان مقاله | کاربردهای زیست پزشکی هیدروژل کاراگینان آغشته به نانوذرات اکسید روی |
عنوان انگلیسی مقاله | Biomedical applications of carrageenan hydrogel impregnated with zinc oxide nanoparticles |
انتشار | مقاله سال ۲۰۲۲ |
تعداد صفحات مقاله انگلیسی | ۱۲ صفحه |
هزینه | دانلود مقاله انگلیسی رایگان میباشد. |
پایگاه داده | نشریه تیلور و فرانسیس – Taylor & Francis |
نوع نگارش مقاله | مقاله پژوهشی (Research article) |
مقاله بیس | این مقاله بیس میباشد |
نمایه (index) | JCR – Master Journal List – Scopus |
نوع مقاله |
ISI |
فرمت مقاله انگلیسی | |
ایمپکت فاکتور(IF) |
۱٫۶۰۴ در سال ۲۰۲۰ |
شاخص H_index | ۴۵ در سال ۲۰۲۲ |
شاخص SJR | ۰٫۲۴۴ در سال ۲۰۲۰ |
شناسه ISSN | ۲۴۷۰-۱۵۶۴ |
شاخص Quartile (چارک) | Q4 در سال ۲۰۲۰ |
فرضیه | ندارد |
مدل مفهومی | دارد |
پرسشنامه | ندارد |
متغیر | ندارد |
رفرنس | دارد |
رشته های مرتبط | داروسازی – پزشکی |
گرایش های مرتبط | نانوفناوری دارویی |
نوع ارائه مقاله |
ژورنال |
مجله / کنفرانس | شیمی معدنی و نانو فلزات – Inorganic and Nano-Metal Chemistry |
دانشگاه | Centre of Advanced Study in Marine Biology, Annamalai University, India |
کلمات کلیدی | هیدروژل – آنتی باکتریال – آنتی بیوفیلم – C/ZnONPs – پانسمان زخم |
کلمات کلیدی انگلیسی | hydrogel – antibacterial – antibiofilm – C/ZnONPs – wound dressing |
شناسه دیجیتال – doi | https://doi.org/10.1080/24701556.2021.1952243 |
کد محصول | e16653 |
وضعیت ترجمه مقاله | ترجمه آماده این مقاله موجود نمیباشد. میتوانید از طریق دکمه پایین سفارش دهید. |
دانلود رایگان مقاله | دانلود رایگان مقاله انگلیسی |
سفارش ترجمه این مقاله | سفارش ترجمه این مقاله |
فهرست مطالب مقاله: |
Abstract Introduction Materials and methods DPPH Microbial studies Result and discussion Microbial studies Conclusion Acknowledgements References |
بخشی از متن مقاله: |
Abstract Nanotechnology involving biopolymers is comprehensively used in biomedical applications, planning sciences, and food development. The present work describes the synthesis, characterization, and application of carrageenan and zinc oxide nanoparticles (ZnONPs) based hydrogel. The synthesized hydrogels were subsequently characterized using FTIR, XRD, SEM, and TG-DTA. The swelling property, antioxidant activity, and whole blood clotting effectiveness of the Carrageenan hydrogel, and Carrageenan Hydrogels Impregnated with Zinc Oxide Nanoparticles were evaluated. The Carrageenan + ZnONPs (C/ZnONPs) hydrogels showed good antioxidant, and blood clotting activity than the pure carrageenan hydrogel. In addition, the stable C/ZnONPs hydrogels exhibit good antimicrobial activities against both Gram-negative and Gram-positive bacterial strains. Biofilm analysis showed that C/ZnONPs hydrogels have excellent anti-biofilm potential in both inhibition and disruption of preformed biofilm. The obtained results suggested that the carrageenan and Zinc oxide nanoparticles based hydrogel have promising biological applications. Introduction Pathogenic microorganism resistance to frequently used antibiotic substances have become an important health concern in the 21st century. The development of microorganism resistance to antibiotics has significantly increased morbidity and mortality, longer hospitalization and increased health care costs.[1] Resistance is increasing against antibiotics, particularly to the first line, inexpensive, and broad-spectrum antibiotics, but also to the newly developed antibiotics; since the development of novel alternative is necessary.[2,3] In the specific case of wound management there are several reports of the microorganism resistance to the drug used to manage wounds.[4] The role of microbial infections in the development of wound infections is well established, the life threatening nature of the wound infections has maximized its importance in human health. In addition, the cost of medication for wound management is also high.[5,6] Hence the exploration of new substance for the wound management is very important. Conclusion The synthesized C/ZnONPs hydrogels was produced by a simple and efficient method, performing proper swelling capacity and much better mechanical properties. It exhibited better antioxidant, blood clotting activity and also possess excellent antibacterial and biofilm efficacy against B. subtilis, S. aureus, E. coli and K. pneumonia. The present study confirmed that C/ZnONPs hydrogel have multi-potential property. Thus, the present study suggests that this bio-reduction practice is a well suitable system for large-scale production. The blood clotting and biofilm efficacy were tested in this study only at the grassroot stage which needs to be addressed further. |