مقاله انگلیسی رایگان در مورد تاثیر عسل توالانگ بر کیفیت زندگی بیماران – الزویر 2018

Chronic obstructive pulmonary disease (COPD) is a common public health illness with a high prevalence, morbidity and mortality.1 It is the third leading cause of death in the world,2 and the death rate from COPD is increasing rapidly, especially among the elderly.3 COPD is characterized by a progressive, partially reversible airflow obstruction and lung hyperinflation with significant extra pulmonary manifestation that leads to a comorbid condition.4 The airway limitation is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles or gases. Patients with COPD usually present with a chronic cough and copious sputum production for many years. COPD has no cure and is an irreversible disease.5 The patients not only suffer physically and mentally, they also have a poor quality of life. A study by E.A. Regan et al. noted that the quality of life (QoL) in her COPD patients worsened in a five year time period and was associated with increased dyspnea and a reduced walking distance.6 An impaired quality of life was significantly linked to increased medical costs for COPD patients.7 Thus, a positive perception of health and preserving the quality of life should be the goal in caring for these patients apart from the usual clinical treatment.8 There are minimal published clinical studies evaluating at the effects of Tualang honey on COPD patients. Based on animal studies, honey has antimicrobial properties and significantly reducesmacrophage recruitment in the airway following inflammatory response due to cigarette smoke inhalation.9 It is hypothesized that honey might have a beneficial effect on COPD patients by improving airway relief, symptoms, nutritional status and, subsequently, quality of life. Therefore, this study aimed to assess the efficacy of Tualang honey in COPD patients in terms of nutritional status, pulmonary function and quality of life. In addition, a further assessment on the safety of honey provides additional scientific information on the usefulness of honey, specifically in COPD patients.