مقاله انگلیسی رایگان در مورد مطالعات بافت شناسی و ایمنی سنجی قانونی – هینداوی 2017

In-custody deaths represent an important problem to the judicial system and to the decedent’s family members [1, 2]. These cases often occur without an obvious cause for the deaths and are labeled death by natural causes. Potential explanations include trauma, suicide, excited delirium, mechanical asphyxia, stress cardiomyopathy, and seizures. In younger decedents, underlying medical disorders are unlikely to contribute to death, in contrast to older individuals with chronic medical conditions. The evaluation of these cases requires a comprehensive approach, but there is a frequent concern that the forensic pathology is casual and biased towards the judicial system [3]. It is particularly difficult to establish the cause of death when the decedent has excited delirium, stress cardiomyopathy, or sudden death from epilepsy. In addition, it may be difficult to establish the cause of death when the etiology involves mechanical asphyxia done in a manner which creates little postmortem evidence of external trauma. Forensic pathologists need to do a thorough external and internal organ evaluation and selected histologic studies. It is possible that molecular studies can help identify unusual causes of death which might be attributed to natural causes. In this review, we consider histological studies and molecular studies which could contribute to the identification of death associated with excited delirium, stress cardiomyopathy, drowning, asphyxia, and possibly seizures.