مقاله انگلیسی رایگان در مورد شيوع آنتي ژن اریتروسیت ۱ سگ در ۷۴۱۴ سگ در ایتالیا – هینداوی ۲۰۱۷
مشخصات مقاله | |
انتشار | مقاله سال ۲۰۱۷ |
تعداد صفحات مقاله انگلیسی | ۱۱ صفحه |
هزینه | دانلود مقاله انگلیسی رایگان میباشد. |
منتشر شده در | نشریه هینداوی |
نوع مقاله | ISI |
عنوان انگلیسی مقاله | Prevalence of Dog Erythrocyte Antigen 1 in 7,414 Dogs in Italy |
ترجمه عنوان مقاله | شيوع آنتي ژن اریتروسیت ۱ سگ در ۷۴۱۴ سگ در ایتالیا |
فرمت مقاله انگلیسی | |
رشته های مرتبط | دامپزشکی |
گرایش های مرتبط | ایمنی شناسی دامپزشکی، علوم آزمایشگاهی دامپزشکی، جراحی دامپزشکی |
مجله | داروی دامپزشکی – Veterinary Medicine International |
دانشگاه | Veterinary Transfusional Center (CTV) – Department of Veterinary Sciences |
کد محصول | E6325 |
وضعیت ترجمه مقاله | ترجمه آماده این مقاله موجود نمیباشد. میتوانید از طریق دکمه پایین سفارش دهید. |
دانلود رایگان مقاله | دانلود رایگان مقاله انگلیسی |
سفارش ترجمه این مقاله | سفارش ترجمه این مقاله |
بخشی از متن مقاله: |
۱٫ Introduction
Canine blood groups are recognized and have standardized terminology as Dog Erythrocyte Antigen (DEA). The DEA system includes seven well-known blood groups (DEA 1, 3, 4, 5, 6, 7, and 8) with over twenty antigen specificities [1–۴]. Other nonstandardized antigens within DEA such as Dal [3, 5] and the recently described Kai 1 and 2 have been reported [6]. Canine blood groups comprise a two-allele system with a positive and negative type. The DEA 1 blood group system initially was described with 3 types, DEA 1.1, 1.2, and likely 1.3 [3, 7, 8]. Utilizing quantitative flow cytometry and an immunochromatographic technique with a monoclonal anti-DEA 1 alloantibody the continuum of DEA 1 negative to weakly (1+) up to strongly DEA 1 positive (4+) blood type was observed in contrast to the originally described DEA 1 system and with a significant correlation between these tests [9]. Recently, an autosomal dominant mode of inheritance of 4 alleles of DEA 1 with strong (4+) to weak (1+) reactivity was discovered. DEA 1 positive alleles are dominant over DEA 1 negative allele without any direct correlation with the historical DEA 1.2 positive subtype [10]. So now, it is accepted to speak about the DEA 1 group as a whole without any subtype [9, 10]. Natural occurring antibodies against DEA 1 antigen in dog’s erythrocytes have never been positively identified [11]. On the other hand, natural antibodies against DEA 3, 5, and 7 have been documented with a prevalence of 6%, 23%, and 45%, respectively [2]. However, although all canine blood group antigens can stimulate the formation of alloantibodies, DEA 1 seems to be the most immunogenic and also is considered the most clinically important. Alloantibodies will appear following the first transfusion in DEA 1 negative recipient dogs receiving positive DEA 1 red blood cells (RBCs) within 4–۱۴ days [11–۱۴]. Sensitization of the recipient and production of alloantibodies can result in a severe acute hemolytic transfusion reaction and even death if a second DEA 1 positive RBC transfusion is administered to the same patient [15–۱۷]. The risk of alloantibody production and transfusion reactions against antigens other than DEA 1 is Hindawi Veterinary Medicine International Volume 2017, Article ID 5914629, 10 pages https://doi.org/10.1155/2017/5914629 2 Veterinary Medicine International not yet well defined [2] and there is no documented clinical evidence of a hemolytic reaction caused by DEA 1.2, 3, 5, and 7 in mismatched transfusions [18]. Blood typing to identify the presence of DEA 1 and the cross-match to establish full compatibility should be performed before each transfusion in order to reduce the risk of sensitization or immunological reaction between donor and recipient dogs [2, 19, 20]. |