مقاله انگلیسی رایگان در مورد خدمات ارائه گواهی محضری و رسمی مبتنی بر بلاک چین – الزویر 2018

Keywords

1- Introduction

2- Background & Related Work

3- The Query Notary Service

4- Cost Analysis Experiments

5- Implementation

6- Discussion Acknowledgment

References

Abstract

Biomedical research and clinical decision depend increasingly on scientific evidence realized by a number of authoritative databases, mostly public and continually enriched via peer scientific contributions. Given the dynamic nature of biomedical evidence data and their usage in the sensitive domain of biomedical science, it is important to ensure retrieved data integrity and non-repudiation. In this work, we present a blockchain-based notarization service that uses smart digital contracts to seal a biomedical database query and the respective results. The goal is to ensure that retrieved data cannot be modified after retrieval and that the database cannot validly deny that the particular data has been provided as a result of a specific query. Biomedical evidence data versioning is also supported. The feasibility of the proposed notarization approach is demonstrated using a real blockchain infrastructure and is tested on two different biomedical evidence databases: a publicly available medical risk factor reference repository and on the PubMed database of biomedical literature references and abstracts.

Introduction

Biomedical research and clinical practice rely increasingly on authoritative data gathered and curated in reference biomedical databases. Examples include: clinical databases (registries or academic clinical databases) that hold clinical data on patient cohorts [1]; biomedical databases [2] with current data on pharmaceuticals [3], metabolomics [4], inheritance data and other omics (for example, the rich collection available from the European Bioinformatics Institute at http://www.ebi.ac.uk/services); publication repositories and other medical evidence repositories [5], either general purpose (the most prominent example being PubMed service by the National Library of Medicine, USA) or high evidence quality, such as Cochrane Library reports.