مقاله انگلیسی رایگان در مورد تشنج ناشی از تب و سندرم مرتبط با آن – الزویر ۲۰۱۸

Febrile seizures are the most common paroxysmal episode during childhood, affecting up to one to de 10 children. Febrile seizures (FS) are among the most common reasons that patients present with to pediatric emergencies. FS has been recognized as a separate disease entity from other type of seizures since the early mid-nineteenth century. These seizures are classically associated with high fever in children during their lives (Hirtz et al., 2003). Their etiology and pathophysiological pathways are being understood better over time; however, there is still more to learn. Genetic predisposition is thought to be a major contributor leading to an increased susceptibility to seizure (Lennox, 1949). Febrile seizures have been historically classified as benign; however, many emerging febrile seizure syndrome behave differently. Lennox was the first clinician to study the background and risk factors for FS and the risk of progression to epilepsy (Lennox, 1949). The American Academy of Pediatricś (AAP) committee of quality improvement published the first evidence-based practice parameters for FS (Baumann & Duffer, 2000). The International League Against Epilepsy (ILAE) then developed a clearer consensus regarding the recognition and treatment of children with FS (Capovilla, Mastrangelo, Romero, & Vigevano, 2009). More recently, the American Academy Pediatrics (AAP) has announced a standard definition of febrile seizures as any seizure associated with fever of > 38 °C (rectal or tympanic), but without central nervous infection (CNS), metabolic disturbance or history of afebrile seizures, in child aged 6 months to 5 years (American Academy of Pediatrics, 2008).They are the result of a particular sensitive to fever in the developing brain, have a mayor genetic predisposition, and nearly always have a being outcome.